HORDB

General Information

ID: hor000026
Uniprot ID: NA
Protein name: Phormia terraenovae hypertrehalosaemic hormone
Gene name: NA
Organism: Protophormia terraenovae
Family: AKH/HRTH/RPCH family
Source: Animal
Expression: cells in the corpora cardiaca
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: ELTFSPDW
Length: 8
Propeptide: NA
Signal peptide: NA
Modification: T1 Pyrrolidone carboxylic acid amide;T8 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Caused an increase in the hemolymph carbohydrate concentration
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000026_AF2.pdb

hor000026_ESM.pdb

Physical Information

Mass:	111910	Formula:	C47H63N9O15
Absent amino acids:	ACGHIKMNQRVY	Common amino acids:	DEFLPSTW
pI:	3.55	Basic residues:	0
Polar residues:	2	Hydrophobic residues:	3
Hydrophobicity:	-55	Boman Index:	-1127
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	48.75
Instability Index:	6967.5	Extinction Coefficient cystines:	5500
Absorbance 280nm:	785.71

Literature

PubMed ID: 2386478
Title: Isolation and Structure of a Novel Charged Member of the Red-Pigment-Concentrating Hormone-Adipokinetic Hormone Family of Peptides Isolated From the Corpora Cardiaca of the Blowfly Phormia Terraenovae (Diptera)